These are both new medications for me. The flexeril is a 30 day letters the nabumetone is long term. Been taking the flexeril 21 days just started nabumetone today. The nabumetone has made me sleepy but i still surface sore all over.
Answers:    Yes you can take them together.
Nabumetone (Relafen) is a NSAID, non-steroidal anti-inflammatory drug.
Cyclobenzaprine HCl (Flexeril) is a long acting muscle relaxer. Cyclobenzaprine is structurally related to the first-generation tricyclic antidepressants like Elavil.
Most credible, it's the Flexeril that is making you sleepy. Relafen is in the same category as Advil (ibuprofen), Aleve (naproxen sodium), Orudis (ketoprofen), etc and there's zilch sedating about it.

Be sure to take the Relafen with food. NSAIDs are complicated on your stomach and can cause an ulcer.

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